Acitretin  cas 55079-83-9 (jerryzhang001@chembj.com) - Nanjing Bangnuo Biotechnology Co., Ltd.

Acitretin  cas 55079-83-9 (jerryzhang001@chembj.com)

PRICE: 5 USD
Company:
Nanjing Bangnuo Biotechnology Co., Ltd.
Contact Person:
Jerry Zhang
Phone:
86-25-52198306


Product Description

Acitretin  CAS 55079-83-9


Chemical information
Product name:Acitretin
CAS No.:55079-83-9
Molecular formula:C21H26O3
Molecular weight:326.43
Product Specifications:Pharmacopoeial grade

 

 Description

Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid. It is taken orally, and is typically used for psoriasis.

It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2=120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days. However, because acitretin can be reverse metabolised into etretinate which has an extremely long half-life, women must avoid becoming pregnant for at least 3 years after discontinuing acitretin. Therefore, acitretin is generally not recommended for women of child-bearing age with a risk of becoming pregnant.


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