Amorolfine Hci/ Morpholine,/hydrochloride cas 78613-38-4   (jerryzhang001@chembj.com) - Nanjing Bangnuo Biotechnology Co., Ltd.

Amorolfine Hci/ Morpholine,/hydrochloride cas 78613-38-4   (jerryzhang001@chembj.com)

PRICE: 5 USD
Company:
Nanjing Bangnuo Biotechnology Co., Ltd.
Contact Person:
Jerry Zhang
Phone:
86-25-52198306


Product Description

Safe and Super Pure 99% Amorolfine hydrochloride/ AMOROLFINE HCL/Amorolfine HCI/ Morpholine,/hydrochloride CAS 78613-38-4  for Antifungal Treatment

Description

 

Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes. Marketed as CuranailLocerylLocetar, and Odenil, amorolfine is commonly available in the form of a nail lacquer, containing 5% amorolfine as the active ingredient.

 

Application

It is used to treat onychomycosis (fungal infection of the toe- and fingernails). Amorolfine 5% nail lacquer in once-weekly or twice-weekly applications has been shown in two studies to be between 60% and 71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment) were 38% and 46%. However, full experimental details of these trials were not available and since they were first reported in 1992 there have been no subsequent trials.

It is a topical solution for the treatment of toenail infections. Systemictreatments may be considered more effective.

 


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