Beta-amyloid (1-42) Human For The Pathology Of Alzheimer Disease cas No.107761-42-2 - Nanjing Bangnuo Biotechnology Co., Ltd.

Beta-amyloid (1-42) Human For The Pathology Of Alzheimer Disease cas No.107761-42-2

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Nanjing Bangnuo Biotechnology Co., Ltd.
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Jerry Zhang
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Product Description

Injectable Beta-Amyloid (1-42) human for the pathology of Alzheimer disease CAS NO.107761-42-2

1. quick detail :

Product Name:    Beta-Amyloid (1-42), Ultra Pure, HFIP  

Catalog #:              P2000022
Storage:             -20°

Molecular Mass:  4514.1 4

Peptide Purity:      98% 

Counter Ion:          HFIP treated 

Supplied As:          No salt, as HFIP desalts the sample.     
Recombinant. A DNA sequence encoding the human beta-amyloid  (1-42)sequence was expressed in E. coli.  

Sequence:   

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala- Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala 

Description:   

Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of  Alzheimer’s Disease (AD)1-3. AD is the most common neurodegenerative disease and afflicts about 10% of the population over 60 4. The abeta,HFIP is described in Stine, et. al.3.

1) Yankner, BA, et. al., (1990) Science, 250: 279-282 

2) Selkoe, D.J., (2001) Physiol. Rev, 81: 741-766    

3) Stine, W.B. et. al., (2003) J. Biol. Chem, 278: 11612-11622

4) Frank, R.A., et. al., (2003) Neurobiology of Aging, 24: 521-536  

 

 

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