Esomeprazole magnesium CAS 161973-10-0
Magnesium,bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, (T-4)- Synonyms:Magnesium,bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]-,[T-4-(S),(S)]-; (-)-Omeprazole magnesium; (S)-Omeprazole magnesium; H 199/18; Nexium; Perprazole; Raciper;
CAS Registry Number:161973-10-0
Boiling Point:600 ºC at 760 mmHg
Flash Point:316.7 ºC
Esomeprazole sold under the brand name Nexium among others, is a proton-pump inhibitor which reduces stomach acid. It is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.
It decreases secretion of acid through inhibition of the H+/K+-ATPase in the parietal cells of the stomach. By inhibiting the functioning of this transporter, the drug prevents formation of stomach acid.
Esomeprazole is the (S)-(−)-enantiomer of omeprazole. Esomeprazole is currently sold over the counter in the US and the UK.