Exemestane Cas 107868-30-4 For Fighting Breast Cancer (jerryzhang001@chembj.com) - Nanjing Bangnuo Biotechnology Co., Ltd.

Exemestane Cas 107868-30-4 For Fighting Breast Cancer (jerryzhang001@chembj.com)

PRICE: 5 USD
Company:
Nanjing Bangnuo Biotechnology Co., Ltd.
Contact Person:
Jerry Zhang
Phone:
86-25-52198306


Product Description

Super Pure 98% min. Muscle Building Bulking Cycle Anti Estrogen Aromasin Steroids Exemestane CAS 107868-30-4 For Fighting Breast Cancer

 

pplications:

 

Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.

 

The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.

 

Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.

Other products
Join Free