Oral Safe and Super Pure 99% Lapatinib CAS 231277-92-2 for Breast Cancer Treatment
Purity : 99%
CAS : 231277-92-2
Grade: Oral pharmaceutical intermediate
Place of Origin: China
Brand Name: NJBNSteroid
Usage : Lapatinib is an orally active drug for breast cancer and other solid tumours. It is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway. It is used in combination therapy for HER2-positive breast cancer. It is used for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2 (ErbB2).
Lapatinib is a breast cancer targeted therapy drug, it is a tyrosine kinase inhibitor, which can inhibit the human epidermal growth factor receptor -1 (ErbB1) and human epidermal growth factor receptor -2 (ErbB2) tyrosine kinase activity. It is unique because it can play a role in a variety of ways, so that the breast cancer cells can not receive the desired signal for the growth . The mechanism is inhibiting the ATP site of intracellular EGFR(ErbB-1) and HER2 (ErbB-2) to prevent phosphorylation and activation of tumor cells, blocking down signal by EGFR (ErbB-1) and homogenous HER2 (ErbB-1) and its heterodimer.